Mortality and causes of death in patients with Parkinson's disease: a nationwide population-based cohort study.

ABSTRACT:

Objective

Parkinson's disease (PD) is a neurodegenerative disease involving multiple systems that can affect mortality. This study aimed to compare all-cause and cause-specific mortality between people with PD and without PD.

Methods

This population-based prospective cohort study is based on Korean National Health Insurance Service data. The primary outcome was the hazard ratio (HR) of all-cause and cause-specific mortality for PD from 2010 to 2019. Cox proportional hazards regression was applied to calculate HRs under crude and three adjusted models with epidemiologic variables.

Results

A total of 8,220 PD patients and 41,100 age- and sex-matched controls without PD were registered. Ten-year mortality was 47.9% in PD patients and 20.3% in non-PD controls. The mortali

SUBMITTER: Ryu DW 

PROVIDER: S-EPMC10501780 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature