Genetic atlas of hygro-and thermosensory cells in the vinegar fly Drosophila melanogaster.

ABSTRACT: The ability of animals to perceive and respond to sensory information is essential for their survival in diverse environments. While much progress has been made in understanding various sensory modalities, the sense of hygrosensation, which involves the detection and response to humidity, remains poorly understood. In this study, we focused on the hygrosensory, and closely related thermosensory, systems in the vinegar fly Drosophila melanogaster to unravel the molecular profile of the cells of these senses. Using a transcriptomic analysis of over 37,000 nuclei, we identified twelve distinct clusters of cells corresponding to temperature-sensing arista neurons, humidity-sensing sacculus neurons, and support cells relating to these neurons. By examining the expression of known and novel mark

SUBMITTER: Corthals K 

PROVIDER: S-EPMC10502013 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature