Effectiveness of COVID-19 vaccination during pregnancy by circulating viral variant.

ABSTRACT:

Background

SARS-CoV-2 infection in pregnancy can result in a spectrum of asymptomatic to critical COVID-19 outcomes, including hospitalization, admission to the intensive care unit, or death.

Objective

This study aimed to investigate the effectiveness of messenger RNA COVID-19 vaccination during pregnancy against both hospitalization and infection, stratified by different variant circulations and by time since the last vaccine dose.

Study design

This was a retrospective cohort study among pregnant persons who were members of Kaiser Permanente Northern California and delivered between December 15, 2020, and September 30, 2022. Pregnant persons who received any vaccine dose before the pregnancy onset date were excluded. The primary outcome was hospitalization for COVID-

SUBMITTER: Zerbo O 

PROVIDER: S-EPMC10502365 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature