Extent of piriform cortex resection in children with temporal lobe epilepsy.

ABSTRACT:

Objective

A greater extent of resection of the temporal portion of the piriform cortex (PC) has been shown to be associated with higher likelihood of seizure freedom in adults undergoing anterior temporal lobe resection (ATLR) for drug-resistant temporal lobe epilepsy (TLE). There have been no such studies in children, therefore this study aimed to investigate this association in a pediatric cohort.

Methods

A retrospective, neuroimaging cohort study of children with TLE who underwent ATLR between 2012 and 2021 was undertaken. The PC, hippocampal and amygdala volumes were measured on the preoperative and postoperative T1-weighted MRI. Using these volumes, the extent of resection per region was compared between the seizure-free and not seizure-free groups.

Results

In 50

SUBMITTER: Piper RJ 

PROVIDER: S-EPMC10502684 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature