Radiomics analysis of amide proton transfer-weighted and structural MR images for treatment response assessment in malignant gliomas.

ABSTRACT: The purpose of this study was to evaluate the value of amide proton transfer-weighted (APTw) MRI radiomic features for the differentiation of tumor recurrence from treatment effect in malignant gliomas. Eighty-six patients who had suspected tumor recurrence after completion of chemoradiation or radiotherapy, and who had APTw-MRI data acquired at 3 T, were retrospectively analyzed. Using a fluid-attenuated inversion recovery (FLAIR) image-based mask, radiomics analysis was applied to the processed APTw and structural MR images. A chi-square automatic interaction detector decision tree was used for classification analysis. Models with and without APTw features were built using the same strategy. Tenfold cross-validation was applied to obtain the overall classification performance of each mod

SUBMITTER: Jiang S 

PROVIDER: S-EPMC10502874 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature