Rubella virus genotype 2B endemicity and related utility of serum-based molecular characterization in Uganda.

ABSTRACT: There are 13 globally recognized rubella virus genotypes of which only 2 (1E and 2B) have been detected recently. The largest percentage of all reported rubella virus sequences come from China and Japan with Africa reporting limited data. In a bid to address the lack of rubella genotype data in Uganda and the World Health Organization Africa region, we sought to characterize rubella viruses retrospectively using sera collected from suspected measles patients that turned out rubella IgM positive.Seven sequences belonging to genotype 2B sub-lineage 2B-L2c were obtained. These sequences clustered with other genotype 2B sequences previously reported from Uganda. None of the other genotypes (1E and 1G) reported from Uganda in the earlier years were detected. In addition, none of the sequences w

SUBMITTER: Tushabe P 

PROVIDER: S-EPMC10503080 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature