Association between adiposity and facial aging: results from a Mendelian randomization study.

ABSTRACT:

Background

Skin, as a sociologically meaningful interface, has psychological implications different from other organs, particularly in the context of the global population aging. Growing evidence suggests that facial aging is associated with an increased risk of adiposity. Existing research, however, were observational, and while they may find some correlations, it is difficult to simply disentangle non-causal or reverse-causal links because these associations may be confounded or fail to accurately reflect true causative linkages.

Objectives

We conducted a 2-sample Mendelian randomization (MR) study to examine the potential effect of facial aging on the risk of broad obesity and its three major adiposity indicators, including body mass index (BMI), body fat percentage (BF%)

SUBMITTER: Liu M 

PROVIDER: S-EPMC10503104 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature