Causes of hypercapnic respiratory failure: a population-based case-control study.

ABSTRACT:

Objective

There are no population-based data on the relative importance of specific causes of hypercapnic respiratory failure (HRF). We sought to quantify the associations between hospitalisation with HRF and potential antecedent causes including chronic obstructive pulmonary disease (COPD), obstructive sleep apnea, and congestive cardiac failure. We used data on the prevalence of these conditions to estimate the population attributable fraction for each cause.

Methods

A case-control study was conducted among residents aged ≥ 40 years from the Liverpool local government area in Sydney, Australia. Cases were identified from hospital records based on PaCO₂ > 45 mmHg. Controls were randomly selected from the study population using a cluster sampling design. We collec

SUBMITTER: Chung Y 

PROVIDER: S-EPMC10503117 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature