Left ventricular remodelling in rheumatic heart disease - trends over time and implications for follow-up in childhood.

ABSTRACT:

Background

Rheumatic heart disease (RHD) is the most common form of acquired heart disease worldwide. In RHD, volume loading from mitral regurgitation leads to left ventricular (LV) dilatation, increased wall stress, and ultimately LV dysfunction. Improved understanding of LV dynamics may contribute to refined timing of intervention. We aimed to characterize and compare left ventricular remodelling between rheumatic heart disease (RHD) severity groups by way of serial echocardiographic assessment of volumes and function in children.

Methods

Children with RHD referred to Perth Children's Hospital (formally Princess Margaret Hospital) (1987-2020) were reviewed. Patients with longitudinal pre-operative echocardiograms at diagnosis, approximately 12 months and at most recent fol

SUBMITTER: MacDonald B 

PROVIDER: S-EPMC10503178 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature