The effect of smoking on MRI lesion resolution in NMOSD-AQP4 and MOGAD.

ABSTRACT:

Background

The effect of smoking on the resolution of magnetic resonance imaging (MRI) lesions in patients with neuromyelitis optica spectrum disorders with aquaporin-4 positive antibody (NMOSD-AQP4) and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) has not been studied before.

Objective

We aimed to determine the effect of smoking on lesion resolution in MRI and assess its correlation with clinical recovery after a relapse.

Methods

We conducted a cohort study including NMOSD-AQP4 and MOGAD patients with acute and follow-up MRI scans. We collected demographic, clinical, imaging and smoking data. Logistic regression models were fitted to predict the effect of smoking on lesion resolution and to assess whether clinical recovery was associated wi

SUBMITTER: Berhanu D 

PROVIDER: S-EPMC10503243 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature