Incidence and Importance of Calcium Deposition in Kidney Biopsy Specimens.

ABSTRACT:

Introduction

Calcification on native kidney biopsy specimens is often noted by pathologists, but the consequence is unknown.

Methods

We searched the pathology reports in the Biopsy Biobank Cohort of Indiana for native biopsy specimens with calcification.

Results

Of the 4,364 specimens, 416 (9.8%) had calcification. We compared clinical and histopathology findings in those with calcification (n = 429) compared to those without calcification (n = 3,936). Patients with calcification were older, had more comorbidities, lower estimated glomerular filtration rates (eGFR), were more likely to have hyaline arteriosclerosis, interstitial fibrosis/tubular atrophy, and a primary pathologic diagnosis of acute tubular injury or acute tubular necrosis when compared to patients with

SUBMITTER: Gaddy A 

PROVIDER: S-EPMC10503271 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature