The dorsal root ganglion as a target for neurorestoration in neuropathic pain.

ABSTRACT: Neuropathic pain is a severe and chronic condition widely found in the general population. The reason for this is the extensive variety of damage or diseases that can spark this unpleasant constant feeling in patients. During the processing of pain, the dorsal root ganglia constitute an important region where dorsal root ganglion neurons play a crucial role in the transmission and propagation of sensory electrical stimulation. Furthermore, the dorsal root ganglia have recently exhibited a regenerative capacity that should not be neglected in the understanding of the development and resolution of neuropathic pain and in the elucidation of innovative therapies. Here, we will review the complex interplay between cells (satellite glial cells and inflammatory cells) and factors (cytokines, neur

SUBMITTER: Estivill-Torrus G 

PROVIDER: S-EPMC10503598 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature