Flares in Lupus Nephritis: Risk Factors and Strategies for Their Prevention.

ABSTRACT:

Purpose of review

Discuss the prognostic significance of kidney flares in patients with lupus nephritis, associated risk factors, and possible preventative strategies.

Recent findings

Recently performed clinical trials and observational cohort studies underscore the high frequency of relapses of kidney disease, following initial response, in patients with proliferative and/or membranous lupus nephritis. Analysis of hard disease outcomes such as progression to chronic kidney disease or end-stage kidney disease, coupled with histological findings from repeat kidney biopsy studies, have drawn attention to the importance of renal function preservation that should be pursued as early as lupus nephritis is diagnosed. In this respect, non-randomized and randomized evidence have sug

SUBMITTER: Banos A 

PROVIDER: S-EPMC10504124 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature