Factors associated with embryo mosaicism: a systematic review and meta-analysis.

ABSTRACT:

Purpose

Evaluate which factors are involved in the increased rate of mosaicism in embryos.

Methods

A systematic review and meta-analysis was performed. After an exhaustive search of the literature, a total of seven papers were included in the analysis. In addition, data collected from IVF cycles performed in our fertility clinic were also analysed. Day of biopsy, embryo quality, maternal and paternal age and seminal quality were the chosen factors to be studied.

Results

The results of the meta-analysis show that neither embryo quality nor seminal quality were related to mosaic embryo rate (OR: 1.09; 95% CI: 0.94-1.28 and OR: 1.10; 95% CI: 0.87-1.37, respectively). A positive association was observed for the variable "biopsy day" with embryos biopsied at day 6 or 7 hav

SUBMITTER: Cascales A 

PROVIDER: S-EPMC10504166 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature