Prognosis and management of acute symptomatic seizures: a prospective, multicenter, observational study.

ABSTRACT:

Background

Acute symptomatic epileptic seizures are frequently seen in neurocritical care. To prevent subsequent unprovoked seizures, long-term treatments with antiseizure medications are often initiated although supporting evidence is lacking. This study aimed at prospectively assessing the risk of unprovoked seizure relapse with respect to the use of antiseizure medications. It was hypothesized that after a first acute symptomatic seizure of structural etiology, the cumulative 12-month risk of unprovoked seizure relapse is ≤ 25%.

Methods

Inclusion criteria were age ≥ 18 and acute symptomatic first-ever epileptic seizure; patients with status epilepticus were excluded. Using telephone and mail interviews, participants were followed for 12 months after the acute symptomatic

SUBMITTER: Herzig-Nichtweiß J 

PROVIDER: S-EPMC10504169 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature