Association between cooling temperature and outcomes of patients with heat stroke.

ABSTRACT: This study explored the relationship between body temperature and adverse outcomes in patients with heat stroke to identify the optimal target body temperature within the first 24 h. This retrospective, multicentre study enrolled 143 patients admitted to the emergency department and diagnosed with heat stroke. The primary outcome was the in-hospital mortality rate, while secondary outcomes included the presence and number of damaged organs and neurological sequelae at discharge. A body temperature curve was built using a generalized additive mixed model, and the association between body temperatures and outcomes was established by logistic regression. The threshold and saturation effects were used to explore the targeted body temperature management. Cases were divided into the surviving an

SUBMITTER: Chen L 

PROVIDER: S-EPMC10504196 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature