CHEK2 C1100del mutation associated with papillary renal cell carcinoma type II.

ABSTRACT: CHEK2 mutations have been noted in bone, brain, breast, colon, lung, thyroid, and prostate cancer. Although now reported in both clear cell and non-clear cell renal cancer, we have not found CHEK2 2 mutations reported in the papillary type II subtype (PRCC). Here, we report a 63-year-old female with a PRCC type II with a concomitant CHEK2 C1100del mutation, who is currently in complete remission three years post tumor resection.

SUBMITTER: Lopez SJ 

PROVIDER: S-EPMC10504490 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature