Molecular docking analysis of the tumor protein beta arrestin-1 with oxadiazole compounds.

ABSTRACT: Beta arrestins are a family of adaptor proteins that help in the regulation of signaling and trafficking of various G protein coupled receptors (GPCRs). Six oxadiazole derivatives taken from literature are analyzed for anti-cancer properties. The toxicity profiles of all the drugs were similar to Tamoxifen used as control. Data shows that compounds 2, 4, and 6 exhibited comparably significant molecular interactions with the cancerous protein for further consideration.

SUBMITTER: Sharma V 

PROVIDER: S-EPMC10504516 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature