Fertility treatment increases the risk of preterm birth independent of multiple gestations.

ABSTRACT:

Objective

To investigate the complex interplay between fertility treatment, multiple gestations, and prematurity.

Design

Retrospective cohort study linking the national Center for Disease Control and Prevention infant birth and death data from 2014 to 2018.

Setting

National database from Center of Disease Control and Prevention.

Patients

In total, 19,454,155 live-born infants with gestational ages 22-44 weeks, 114,645 infants born using non IVF fertility treatment (NIFT), and 179,960 via assisted reproductive technology (ART).

Intervention

Noninvasive fertility treatment or ART vs. spontaneously conceived pregnancies.

Main outcome measures

The main outcome assessed was prematurity. Formal mediation analysis was conducted to calculate the percentag

SUBMITTER: Fineman DC 

PROVIDER: S-EPMC10504569 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature