The conditional mitochondrial protein complexome in the Arabidopsis thaliana root and shoot.

ABSTRACT: Protein complexes are important for almost all biological processes. Hence, to fully understand how cells work, it is also necessary to characterize protein complexes and their dynamics in response to various cellular cues. Moreover, the dynamics of protein interaction play crucial roles in regulating the (dis)association of protein complexes and, in turn, regulating biological processes such as metabolism. Here, mitochondrial protein complexes were investigated by blue native PAGE and size-exclusion chromatography under conditions of oxidative stress in order to monitor their dynamic (dis)associations. Rearrangements of enzyme interactions and changes in protein complex abundance were observed in response to oxidative stress induced by menadione treatment. These included changes in enzyma

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC10504587 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature