Bipolar At-Risk Criteria and Risk of Bipolar Disorder Over 10 or More Years.

ABSTRACT:

Importance

Predicting the onset of bipolar disorder (BD) could facilitate preventive treatments. Among risk measures, bipolar at-risk (BAR) criteria have shown promise in predicting onset of bipolar disorder in the first year in clinical cohorts; however, it is not known whether BAR criteria are associated with the onset of BD in the longer term.

Objective

To assess the association of BAR criteria with onset of BD over 10 to 13 years follow-up.

Design, setting, and participants

This prospective cohort study, completed between May 1, 2020, and November 7, 2022, included consenting people seeking help for nonpsychotic major mental health difficulties, including mood, personality, and substance use disorders, who were originally recruited at ages 15 to 25 years from a te

SUBMITTER: Ratheesh A 

PROVIDER: S-EPMC10504610 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature