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Cytogenetic profile of 1791 adult acute myeloid leukemia in India.


ABSTRACT:

Background

Cytogenetic analysis continues to have an important role in the management of acute myeloid leukemia (AML) because it is essential for prognostication. It is also necessary to diagnose specific categories of AML and to determine the most effective form of treatment. Reports from South Asia are few because the availability of cytogenetic services is relatively limited.

Methods

We performed a retrospective analysis of the cytogenetic findings in adults with AML seen consecutively in a single centre in India. The results were categorised according to the 2022 World Health Organisation (WHO), International Consensus Classification (ICC) and European LeukemiaNet (ELN) classifications.

Results

There were 1791 patients aged 18-85 years (median age 42, 1086 males).

SUBMITTER: Srivastava VM 

PROVIDER: S-EPMC10504794 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature