Polymorphism of fucosyltransferase 3 gene is associated with inflammatory bowel disease: a systematic review.

ABSTRACT:

Background

Inflammatory bowel disease (IBD) is a condition with an unclear genetic basis. Fucosyltransferase 3 (FUT3) could potentially be linked to IBD susceptibility.

Objective

To investigate the association between FUT3 gene polymorphisms and IBD.

Methods

Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 checklist and Population, Intervention, Comparison, Outcomes, and Study (PICOS) guidelines, case-control studies published until April 30, 2020 was searched. Two independent reviewers conducted screening, data extraction, and quality assessment using the Newcastle-Ottawa Scale. Meta-analysis, sensitivity analysis, and Egger tests were performed using RevMan and Stata12.0.

Results

The review included 5 artic

SUBMITTER: Zheng J 

PROVIDER: S-EPMC10505062 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature