Preconceptional and prenatal exposure to air pollutants and risk of gestational diabetes in the MADRES prospective pregnancy cohort study.

ABSTRACT:

Background

Air pollution has been associated with gestational diabetes mellitus (GDM). We aim to investigate susceptible windows of air pollution exposure and factors determining population vulnerability.

Methods

We ascertained GDM status in the prospective Maternal and Developmental Risks from Environmental and Social Stressors (MADRES) pregnancy cohort from Los Angeles, California, USA. We calculated the relative risk of GDM by exposure to ambient particulate matter (PM₁₀; PM_2.5), nitrogen dioxide (NO₂), and ozone (O₃) in each week from 12 weeks before to 24 weeks after conception, adjusting for potential confounders, with distributed lag models to identify susceptible exposure windows. We examined effect modification by prenatal

SUBMITTER: Niu Z 

PROVIDER: S-EPMC10505827 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature