Comparative effectiveness of interventions for preventing tuberculosis: systematic review and network meta-analysis of interventional studies.

ABSTRACT:

Background

Tuberculosis (TB) is the leading infectious cause of death globally. Several preventive measures are employed to prevent TB, yet there is a paucity of evidence on the effectiveness of these interventions. Therefore, this study aimed to identify the most effective interventions for reducing TB incidence.

Methods

A systematic search was undertaken across five relevant databases including PubMed, SCOPUS, Web of Science, Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov from inception to February 22, 2023. Bayesian network meta-analysis (NMA) was conducted to compare the effectiveness of preventive interventions including preventive therapy, nutritional intervention, targeted screening, and vaccination in reducing TB incidence. Subgroup analysis w

SUBMITTER: Liyew AM 

PROVIDER: S-EPMC10507197 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature