Bloodstream infection and ventilator-associated pneumonia in patients with coronavirus disease 2019 (COVID-19) supported by extracorporeal membrane oxygenation.

ABSTRACT:

Objective

Extracorporeal membrane oxygenation (ECMO) has been widely used in the care of patients with respiratory failure from coronavirus disease 2019 (COVID-19). We characterized bloodstream infections (BSIs) and ventilator-associated pneumonias (VAPs) in COVID-19 patients supported with ECMO, and we investigated their impact on patient outcomes.

Design

Retrospective cohort study from March 1, 2020, to June 30, 2021.

Setting

Academic tertiary-care referral center.

Patients

Consecutive adult patients admitted for COVID-19 who received ECMO.

Methods

We identified BSIs and VAPs and described their epidemiology and microbiology. Cumulative antimicrobial use and the specific management of BSIs were determined. Multivariate time-dependent Cox proportional h

SUBMITTER: Tan C 

PROVIDER: S-EPMC10507515 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature