A study of the proteomic expression in patients with complicated parapneumonic pleural effusion.

ABSTRACT:

Introduction

The present study aimed to investigate the differences in the proteomic expression between uncomplicated parapneumonic pleural effusion (UPPE) and complicated parapneumonic pleural effusion (CPPE).

Material and methods

There were 10 patients with UPPE and 10 patients with CPPE. These patients were combined due to the complication of pleural effusion and further divided into group A and group B. An LC-MS analysis was conducted with the extraction of high-abundance proteins, and proteins with 1.5-fold or higher difference multiples were identified as differential proteins. Then, gene ontology (GO) and KEGG analyses were conducted on the differential proteins between the groups.

Results

Compared with the UPPE group, there were 38 upregulated proteins and 29

SUBMITTER: Wu X 

PROVIDER: S-EPMC10507766 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature