Triglyceride-glucose index and the risk of stroke in American adults: findings from the atherosclerosis risk in communities study.

ABSTRACT:

Objectives

The associations between the triglyceride-glucose (TyG) index with subsequent stroke in American adults are unknown. The aim of this study was to determine the associations between baseline and trajectories of TyG index with subsequent stroke in American adults.

Methods

A total of 10,132 participants free of a history of stroke at baseline were included. We quantified the association of baseline and trajectories of TyG index with incident total stroke, ischemic stroke and intracerebral hemorrhage using Cox regression, restricted cubic splines and logistic regression analysis.

Results

There were 909 incident stroke cases over a median follow-up of 26.6 years. After adjustment for potential confounders, each unit increase in the TyG index was associated with

SUBMITTER: Wang X 

PROVIDER: S-EPMC10507886 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature