Structural variation and introgression from wild populations in East Asian cattle genomes confer adaptation to local environment.

ABSTRACT:

Background

Structural variations (SVs) in individual genomes are major determinants of complex traits, including adaptability to environmental variables. The Mongolian and Hainan cattle breeds in East Asia are of taurine and indicine origins that have evolved to adapt to cold and hot environments, respectively. However, few studies have investigated SVs in East Asian cattle genomes and their roles in environmental adaptation, and little is known about adaptively introgressed SVs in East Asian cattle.

Results

In this study, we examine the roles of SVs in the climate adaptation of these two cattle lineages by generating highly contiguous chromosome-scale genome assemblies. Comparison of the two assemblies along with 18 Mongolian and Hainan cattle genomes obtained by long-read

SUBMITTER: Xia X 

PROVIDER: S-EPMC10507960 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature