Dietary sodium restriction reduces blood pressure in patients with treatment resistant hypertension.

ABSTRACT:

Purpose

Patients with treatment resistant hypertension (TRH) are at particular risk of cardiovascular disease. Life style modification, including sodium restriction, is an important part of the treatment of these patients. We aimed to analyse if self-performed dietary sodium restriction could be implemented in patients with TRH and to evaluate the effect of this intervention on blood pressure (BP). Moreover, we aimed to examine if mechanisms involving nitric oxide, body water content and BNP, renal function and handling of sodium were involved in the effect on nocturnal and 24-h BP. Also, measurement of erythrocyte sodium sensitivity was included as a possible predictor for the effect of sodium restriction on BP levels.

Patients and methods

TRH patients were included for thi

SUBMITTER: Hornstrup BG 

PROVIDER: S-EPMC10507975 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature