Racial and Ethnic Differences in the Association between Depressive Symptoms and Cognitive Outcomes in Older Adults: Findings from KHANDLE and STAR.

ABSTRACT:

Introduction

Depressive symptoms are associated with higher risk of dementia but how they impact cognition in diverse populations is unclear.

Methods

Asian, Black, LatinX, or White participants (n=2,227) in the Kaiser Healthy Aging and Diverse Life Experiences (age 65+) and the Study of Healthy Aging in African Americans (age 50+) underwent up to three waves of cognitive assessments over four years. Multilevel models stratified by race/ethnicity were used to examine whether depressive symptoms were associated with cognition or cognitive decline and whether associations differed by race/ethnicity.

Results

Higher depressive symptoms were associated with lower baseline verbal episodic memory scores (-0.06, 95%CI: -0.12, -0.01; -0.15, 95%CI: -0.25, -0.04), and faster decl

SUBMITTER: Jimenez MP 

PROVIDER: S-EPMC10508807 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature