Incidence of perioperative hypersensitivity reactions: A single-center, prospective, US cohort experience.

ABSTRACT:

Background

A previous study, using administrative data, reported an incidence of perioperative anaphylaxis (POA) of 1:6537 procedures in the United States.

Objective

We sought to determine the incidence of POA in a prospective US cohort.

Methods

Adult participants undergoing a procedure at a single tertiary care center were studied prospectively between April 2018 and January 2022. Subinvestigators recorded vital signs and skin checks preoperatively, 15 minutes into induction, and hourly thereafter until 1 hour into the postoperative period. If participants developed an adverse reaction, additional variables were documented: causal agent(s) exposure, type of nonallergic adverse reaction, Sixth National Audit Project severity score, evidence of mast cell activation by

SUBMITTER: Gonzalez-Estrada A 

PROVIDER: S-EPMC10509856 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature