Long-term outcomes of oral immunotherapy for anaphylactic egg allergy in children.

ABSTRACT:

Background

Studies of long-term oral immunotherapy (OIT) in children with anaphylactic egg allergy are limited.

Objective

Our aim was to investigate the long-term outcomes of OIT for anaphylactic egg allergy.

Methods

The participants included children (aged ≥ 5 years) with a history of anaphylaxis in response to eggs and objective reactions to oral food challenge (OFC) with 250 mg of egg protein. In the OIT group, the home starting dose of egg protein set during 5 days of hospitalization was ingested once daily and gradually increased to 1000 mg. Over the next year, participants temporarily discontinued OIT for 2 weeks and underwent OFC with 3100 mg of egg protein annually until they passed. The historical control group comprised patients who did not receive OIT and r

SUBMITTER: Sasamoto K 

PROVIDER: S-EPMC10509875 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature