Maternal antibiotic exposure and childhood allergies: The Japan Environment and Children's Study.

ABSTRACT:

Background

The association of maternal antibiotic exposure during pregnancy with childhood allergic diseases remains unclear.

Objective

We aimed to evaluate the association of maternal exposure to antibiotic use during pregnancy with childhood allergic diseases up to the age of 3 years by using data from a large Japanese birth cohort.

Methods

We analyzed data on 78,678 pregnant women and their offspring aged 0 to 3 years. Prenatal antibiotic exposure was defined as the use of any antimicrobial agent during pregnancy. Information was collected from maternal interviews and medical record transcripts. The outcome variables in this study included preschool asthma, wheezing, food allergy, atopic dermatitis, eczema, allergic rhinoconjunctivitis, and any allergic disease. We

SUBMITTER: Okoshi K 

PROVIDER: S-EPMC10509907 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature