Delabeling, safety, and impact of β-lactam allergy testing: A systematic review.

ABSTRACT:

Background

To improve β-lactam delabeling outcomes, we need to understand current practice and the evidence base regarding its outcomes, safety, and impact.

Objectives

We sought to assess the existing published evidence reporting on the effectiveness of penicillin allergy testing and delabeling.

Methods

We conducted a systematic review of studies reporting β-lactam delabeling practices and outcomes after testing, including β-lactam use and patient understanding of the delabeling result. Searches of the PubMed, Scopus, and Embase databases; clinical trial registries; and websites of professional organizations were conducted. Data were extracted from the included studies in duplicate, with a third extraction if discrepancies remained.

Results

We included 284 publ

SUBMITTER: Loprete J 

PROVIDER: S-EPMC10509936 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature