Sensitization pattern to environmental allergens in a Japanese population.

ABSTRACT:

Background

We previously described the prevalence of allergen-specific IgE in a general population of Japanese adults.

Objective

We sought to elucidate allergen sensitization patterns in this population.

Methods

Serum samples had been obtained from 800 blood donors aged 20 to 59 years and living in Tokyo, Japan, in 2005 and stored in the Japanese Red Cross Society. These samples were examined for IgE levels, total and specific for 23 allergens or allergen sources correlated with allergic airway diseases using the ImmunoCAP method. Exploratory and confirmatory factor analyses were performed to uncover the relationship among allergen-specific IgE based on their titers. Hierarchical cluster analysis was executed using Ward's method based on standardized factor scores ide

SUBMITTER: Kitahara A 

PROVIDER: S-EPMC10509945 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature