Efficacy of Japanese cedar pollen sublingual immunotherapy tablets for Japanese cypress pollinosis.

ABSTRACT:

Background

We previously demonstrated the efficacy of Japanese cedar (JC) pollen sublingual immunotherapy (SLIT) tablets for treating seasonal allergic rhinitis in a clinical trial (trial no. 206-2-1) that covered 5 pollen dispersal seasons from 2015 to 2019.

Objective

Our aim was to perform post hoc analysis of the 206-2-1 trial data to evaluate the efficacy of JC pollen SLIT tablets for patients with rhinitis induced by pollen from Japanese cypress (JCY), a related Cupressaceae species that has a pollen dispersal season overlapping with that of JC.

Methods

Data were analyzed for 240 patients who received placebo during the first pollen dispersal season in 2015, were then rerandomized to receive JC SLIT tablets (the PA group) or placebo (the PP group) for 18 m

SUBMITTER: Kurokawa T 

PROVIDER: S-EPMC10509998 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature