Larval therapy vs conventional silver dressings for full-thickness burns: a randomized controlled trial.

ABSTRACT:

Background

This is the first clinical trial to investigate the effectiveness of maggot debridement therapy (MDT) for full-thickness burn injuries in comparison to conventional silver dressings.

Methods

Thirty-one cases with full-thickness (grade III based on ICD-10 classifications version 2019) burns were assigned into larval therapy (15 cases) and conventional treatment (16 cases) groups. Participants in the MDT group have received loose larvae on days 0, 2, 4, and 6, while controls received a conventional regimen comprised of sharp debridement, silver sulfadiazine, antibiotic therapy, and offloading every day. The primary and secondary outcomes were defined as the time to debridement (from admission to skin autograft) and time to healing (from admission to complete healing

SUBMITTER: Gaffari J 

PROVIDER: S-EPMC10510148 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature