Quantifying the Effect of Guest Binding on Host Environment.

ABSTRACT: The environment around a host-guest complex is defined by intermolecular interactions between the complex, solvent molecules, and counterions. These interactions govern both the solubility of these complexes and the rates of reactions occurring within the host molecules and can be critical to catalytic and separation applications of host-guest systems. However, these interactions are challenging to detect using standard analytical chemistry techniques. Here, we quantify the hydration and ion pairing of a Fe^II₄L₄ coordination cage with a set of guest molecules having widely varying physicochemical properties. The impact of guest properties on host ion pairing and hydration was determined through microwave microfluidic measurements paired with principal compo

SUBMITTER: Ryan HP 

PROVIDER: S-EPMC10510717 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature