Prognostic Value of Modified Coronary Flow Capacity Derived From [¹⁵O]H₂O Positron Emission Tomography Perfusion Imaging.

ABSTRACT:

Background

Coronary flow capacity (CFC) is a measure that integrates hyperemic myocardial blood flow and coronary flow reserve to quantify the pathophysiological impact of coronary artery disease on vasodilator capacity. This study explores the prognostic value of modified CFC derived from [¹⁵O]H₂O positron emission tomography perfusion imaging.

Methods

Quantitative rest/stress perfusion measurements were obtained from 1300 patients with known or suspected coronary artery disease. Patients were classified as having myocardial steal (n=38), severely reduced CFC (n=141), moderately reduced CFC (n=394), minimally reduced CFC (n=245), or normal flow (n=482) using previously defined thresholds. The end point was a composite of death and nonfatal myocardial i

SUBMITTER: de Winter RW 

PROVIDER: S-EPMC10510823 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature