Continuous addition kinetic elucidation: catalyst and reactant order, rate constant, and poisoning from a single experiment.

ABSTRACT: Kinetic analysis of catalytic reactions is a powerful tool for mechanistic elucidation but is often challenging to perform, limiting understanding and therefore development of these reactions. Establishing order in a catalyst is usually achieved by running several reactions at different loadings, which is both time-consuming and complicated by the challenge of maintaining consistent run-to-run experimental conditions. Continuous addition kinetic elucidation (CAKE) was developed to circumvent these issues by continuously injecting a catalyst into a reaction, while monitoring reaction progress over time. For reactions that are mth order in a single yield-limiting reactant and nth order in catalyst, a plot of reactant concentration against time has a shape dependent only on the

SUBMITTER: Williams PJH 

PROVIDER: S-EPMC10510844 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature