Associations between immune-mediated diseases (IMDs) and the risk of HPV-associated diseases: a UK Biobank cohort analysis.

ABSTRACT:

Objectives

To systematically assess the associations between various immune-mediated diseases (IMDs) and human papillomavirus (HPV)-associated diseases.

Design

Retrospective cohort study.

Setting

UK Biobank.

Participants

A total of 500 371 subjects aged 40-69 years were eligible for the analysis, after excluding those with prevalent HPV-associated diseases at baseline and those who had withdrawn their informed consent or lacked information on sex.

Exposure

Eighty IMDs (involving allergic/atopic diseases, autoimmune diseases, immunodeficiency diseases, etc) were identified in the UK Biobank.

Primary and secondary outcome measures

The main outcome was the incidence of HPV-associated diseases (including warts and malignancies of the cervix, oropharyn

SUBMITTER: Feng L 

PROVIDER: S-EPMC10510897 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature