Investigating causal relationships between obesity and skin barrier function in a multi-ethnic Asian general population cohort.

ABSTRACT:

Background

Skin diseases impact significantly on the quality of life and psychology of patients. Obesity has been observed as a risk factor for skin diseases. Skin epidermal barrier dysfunctions are typical manifestations across several dermatological disturbances.

Objectives

We aim to establish the association between obesity and skin physiology measurements and investigate whether obesity may play a possible causal role on skin barrier dysfunction.

Methods

We investigated the relationship of obesity with skin physiology measurements, namely transepidermal water loss (TEWL), skin surface moisture and skin pH in an Asian population cohort (n = 9990). To assess for a possible causal association between body mass index (BMI) and skin physiology measurements, we performe

SUBMITTER: Yew YW 

PROVIDER: S-EPMC10511308 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature