Central obesity and its association with retinal age gap: insights from the UK Biobank study.

ABSTRACT:

Background

Conflicting evidence exists on the association between ageing and obesity. Retinal age derived from fundus images has been validated as a novel biomarker of ageing. In this study, we aim to investigate the association between different anthropometric phenotypes based on body mass index (BMI) and waist circumference (WC) and the retinal age gap (retinal age minus chronological age).

Methods

A total of 35,550 participants with BMI, WC and qualified retinal imaging data available were included to investigate the association between anthropometric groups and retinal ageing. Participants were stratified into 7 different body composition groups based on BMI and WC (Normal-weight/Normal WC, Overweight/Normal WC, Mild obesity/Normal WC, Normal-weight/High WC, Overweight/H

SUBMITTER: Chen R 

PROVIDER: S-EPMC10511312 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature