Current state of radiomic research in pancreatic cancer: focusing on study design and reproducibility of findings.

ABSTRACT:

Objectives

To critically appraise methodology and reproducibility of published studies on CT radiomics of pancreatic ductal adenocarcinoma (PDAC).

Methods

PRISMA literature search of MEDLINE, PubMed, and Scopus databases was conducted from June to August 2022 relating to CT radiomics human research articles pertaining to PDAC diagnosis, treatment, and/ or prognosis, utilising Image Biomarker Standardisation Initiative-compliant (IBSI) radiomic software. Keyword search included [pancreas OR pancreatic] AND [radiomic OR [quantitative AND imaging] OR [texture AND analysis]]. Analysis included cohort size, CT protocol used, radiomic feature (RF) extraction, segmentation, and selection, software used, outcome correlation, and statistical methodology, with focus on reproducibility

SUBMITTER: Malcolm JA 

PROVIDER: S-EPMC10511615 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature