Detection and quantification of breast arterial calcifications on mammograms: a deep learning approach.

ABSTRACT:

Objective

Breast arterial calcifications (BAC) are a sex-specific cardiovascular disease biomarker that might improve cardiovascular risk stratification in women. We implemented a deep convolutional neural network for automatic BAC detection and quantification.

Methods

In this retrospective study, four readers labelled four-view mammograms as BAC positive (BAC+) or BAC negative (BAC-) at image level. Starting from a pretrained VGG16 model, we trained a convolutional neural network to discriminate BAC+ and BAC- mammograms. Accuracy, F1 score, and area under the receiver operating characteristic curve (AUC-ROC) were used to assess the diagnostic performance. Predictions of calcified areas were generated using the generalized gradient-weighted class activation mapping (Grad-CAM

SUBMITTER: Mobini N 

PROVIDER: S-EPMC10511622 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature