Patterns of Genomic Instability in Interspecific Yeast Hybrids With Diverse Ancestries.

ABSTRACT: The genomes of hybrids often show substantial deviations from the features of the parent genomes, including genomic instabilities characterized by chromosomal rearrangements, gains, and losses. This plastic genomic architecture generates phenotypic diversity, potentially giving hybrids access to new ecological niches. It is however unclear if there are any generalizable patterns and predictability in the type and prevalence of genomic variation and instability across hybrids with different genetic and ecological backgrounds. Here, we analyzed the genomic architecture of 204 interspecific Saccharomyces yeast hybrids isolated from natural, industrial fermentation, clinical, and laboratory environments. Synchronous mapping to all eight putative parental species showed significant varia

SUBMITTER: Bendixsen DP 

PROVIDER: S-EPMC10512264 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature