Hortaea werneckii isolates exhibit different pathogenic potential in the invertebrate infection model Galleria mellonella.

ABSTRACT: Hortaea werneckii is a black yeast with a remarkable tolerance to salt. Most studies have been dedicated to understanding how H. werneckii adapts to hypersaline environments. H. werneckii has an unconventional cell cycle in which it alternates between fission and budding, which is modulated by cell density. Additionally, H. werneckii can cause superficial mycosis of the palm and sole of humans. Here, we determine the impact of salt concentration on the EXF-2000 strain's cell division pattern and morphology by performing timelapse microscopy at different salt concentrations. At low density and no salt, EXF-2000 primarily grows as pseudohyphae dividing mainly by septation. When grown in the presence of salt at a similar concentration to saltwater or hypersaline en

SUBMITTER: Anthonies S 

PROVIDER: S-EPMC10512279 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature