Prevalence of hepatitis E virus in China from 1997 to 2022: a systematic review and meta-analysis.

ABSTRACT:

Introduction

Several studies have reported on hepatitis E virus (HEV) prevalence in various regions of China, but the results vary widely. Herein, we conducted a systematic review and meta-analysis to assess the seroprevalence, RNA-positive rate, genotype distribution of HEV in China, and its risk factors.

Methods

We included 208 related studies involving 1,785,569 participants published between 1997 and 2022. Random-effects models were used to pool prevalence, and subgroup analyses were conducted by population, gender, age, study period, regions, and rural-urban distribution. The meta regression models and pooled odds ratios (OR) were performed to identify risk factors for HEV infections.

Results

The pooled anti-HEV IgG, IgM, and Ag seroprevalence, and RNA detection

SUBMITTER: Cao K 

PROVIDER: S-EPMC10512461 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature