Impact of premature coronary artery disease on adverse event risk following first percutaneous coronary intervention.

ABSTRACT:

Objectives

We assessed differences in risk profile and 3-year outcome between patients undergoing percutaneous coronary intervention (PCI) for premature and non-premature coronary artery disease (CAD).

Background

The prevalence of CAD increases with age, yet some individuals develop obstructive CAD at younger age.

Methods

Among participants in four randomized all-comers PCI trials, without previous coronary revascularization or myocardial infarction (MI), we compared patients with premature (men <50 years; women <55 years) and non-premature CAD. Various clinical endpoints were assessed, including multivariate analyses.

Results

Of 6,171 patients, 887 (14.4%) suffered from premature CAD. These patients had fewer risk factors than patients with non-p

SUBMITTER: Pinxterhuis TH 

PROVIDER: S-EPMC10512829 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature